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  • Title: Molecular diagnosis of a benign proliferative nodule developing in a congenital melanocytic nevus in a 3-month-old infant.
    Author: Murphy MJ, Jen M, Chang MW, Grant-Kels JM, Makkar H.
    Journal: J Am Acad Dermatol; 2008 Sep; 59(3):518-23. PubMed ID: 18640742.
    Abstract:
    Small and intermediate congenital melanocytic nevi have a lifetime risk of developing melanoma estimated to range from 0% to 5%. Secondary benign melanocytic proliferations commonly arise in congenital melanocytic nevi; however, some are difficult to definitively distinguish from malignant melanoma based on clinical features and conventional histology. Herein, we describe the use of comparative genomic hybridization in supporting the diagnosis of a deep penetrating nevus developing within a congenital melanocytic nevus of a 3-month-old infant.
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