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  • Title: Interstitial high-dose-rate-brachytherapy in advanced esthesioneuroblastoma.
    Author: Tselis N, Heyd R, Baghi M, Zamboglou N.
    Journal: Laryngoscope; 2008 Nov; 118(11):2006-10. PubMed ID: 18641524.
    Abstract:
    Esthesioneuroblastoma is a rare neuroectodermal tumor of the nasal vault with an aggressive biological behavior that is characterized by local recurrence, atypical distant metastasis, and poor long-term prognosis. The treatment regimen consists of surgical resection, radiation therapy, and chemotherapy in various, mainly stage-dependent, combinations. We report two cases of primary metastatic and locally recurrent disease, which were treated with computed tomography-guided interstitial high-dose-rate brachytherapy in palliative and curative intent, respectively. Computed tomography-guided interstitial high-dose-rate brachytherapy should be considered as a feasible treatment option for advanced esthesioneuroblastoma.
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