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  • Title: Umbilical cord ulceration after prenatal diagnosis of duodenal atresia with interstitial deletion of chromosome 13q: a case report.
    Author: Miyake H, Yamamoto A, Yamada T, Okazaki K, Morita K, Kondo M, Ishida T, Nishina T, Yokota A, Nakai A, Takeshita T.
    Journal: Fetal Diagn Ther; 2008; 24(2):115-8. PubMed ID: 18648211.
    Abstract:
    Umbilical cord ulceration complicated by massive local hemorrhage may be a lethal event in the fetus, and this ulceration has been reported to be associated with upper intestinal atresia. The diagnosis of umbilical cord bleeding is difficult. We present a case of umbilical cord ulceration, hemorrhage, and duodenal atresia which had, in addition, an interstitial deletion of chromosome 13q. A female infant weighing 1,691 g was delivered by cesarean section at 34 weeks of gestation and had resuscitation and laparotomy. Just before the cesarean section, ultrasonography showed a 'double bubble' sign and a linear shadow, suggesting fibrin in the amniotic cavity. This finding may help in the diagnosis of bleeding from the cord.
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