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  • Title: Lung biopsy: special techniques.
    Author: Cham MD, Lane ME, Henschke CI, Yankelevitz DF.
    Journal: Semin Respir Crit Care Med; 2008 Aug; 29(4):335-49. PubMed ID: 18651353.
    Abstract:
    Transthoracic needle biopsy of the indeterminate pulmonary nodule is a well-established, highly accurate, and minimally invasive diagnostic procedure. A pulmonary nodule in virtually any location is accessible to transthoracic needle biopsy. A solid understanding of special biopsy techniques enables the operator to overcome the commonly encountered challenges, including small, mobile, and partly obscured nodules. Because biopsy-related complications can be reduced but not completely eliminated, a familiarity with such complications and the procedures used to manage them is essential. A close partnership with the cytology team is crucial in achieving a high diagnostic accuracy during transthoracic needle biopsy. In the future, biopsy-derived microarray analysis may play a greater role in guiding treatment and predicting treatment outcomes.
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