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  • Title: Controlled patterning of aligned self-assembled peptide nanotubes.
    Author: Reches M, Gazit E.
    Journal: Nat Nanotechnol; 2006 Dec; 1(3):195-200. PubMed ID: 18654186.
    Abstract:
    Controlling the spatial organization of objects at the nanoscale is a key challenge in enabling their technological application. Biomolecular assemblies are attractive nanostructures owing to their biocompatibility, straightforward chemical modifiability, inherent molecular recognition properties and their availability for bottom-up fabrication. Aromatic peptide nanotubes are self-assembled nanostructures with unique physical and chemical stability and remarkable mechanical rigidity. Their application in the fabrication of metallic nanowires and in the improvement of the sensitivity of electrochemical biosensors have already been demonstrated. Here we show the formation of a vertically aligned nanoforest by axial unidirectional growth of a dense array of these peptide tubes. We also achieved horizontal alignment of the tubes through noncovalent coating of the tubes with a ferrofluid and the application of an external magnetic field. Taken together, our results demonstrate the ability to form a two-dimensional dense array of nanotube assemblies with either vertical or horizontal patterns.
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