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  • Title: [Multiple supratentorial cavernomas and epilepsy surgery: case report].
    Author: Rocamora R, Mendivil P, Schulze-Bonhage A.
    Journal: Neurocirugia (Astur); 2008 Jun; 19(3):257-63; discussion 263-6. PubMed ID: 18654726.
    Abstract:
    INTRODUCTION: Epilepsy associated with multiple lesions requires a detailed preoperative evaluation. We report on a patient with 9 cavernous malformations associated with medically intractable seizures who became seizure free after a selective resection of two adjacent cavernous resection. The importance of a detailed neuroradiological and electroencephalographic analysis is stressed. CASE REPORT: The patient was a right-handed 56-year-old woman with a 26-year history of complex partial and secondarily generalized seizures. A non-invasive video EEG monitoring revealed the epileptogenic zone was temporal anterior on the left. A detailed MRI-analysis showed an intact hippocampal formation. An extended lesionectomy of 2 adjacent cavernomas was done. The patient has been free of seizures for 24 months after surgery. CONCLUSIONS: Medically intractable seizures associated with multiple cavernous malformations can be diagnosed by non-invasive preoperative monitoring and controlled by single resective procedures.
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