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  • Title: [Fibrinolysis as a cause of coagulopathy in patients with chronic diffuse diseases of the liver].
    Author: Serov NA, Sukhanov VA, Podymova SD.
    Journal: Klin Med (Mosk); 1991 Apr; 69(4):73-5. PubMed ID: 1865658.
    Abstract:
    Examination was performed of 74 patients with chronic diffuse diseases of the liver; chronic active hepatitis, compensated hepatitis, decompensated cirrhosis of the liver (26, 28, 20 patients, respectively). Fibrinolysis was evaluated in relation to its effect on hemocoagulation. It appeared the principal cause of coagulopathy in 3% of the examinees. It is stated that activated fibrinolysis in chronic diffuse diseases of the liver underlies coagulopathy in few patients with decompensated cirrhosis, in compensated hepatopathy the influence of fibrinolysis on overall coagulative capacity of peripheral blood is insignificant.
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