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  • Title: [Study on antioxidant activity of constituents from mulberry leaf].
    Author: Jiang YL, Piao HS, Li G.
    Journal: Zhong Yao Cai; 2008 Apr; 31(4):519-22. PubMed ID: 18661822.
    Abstract:
    OBJECTIVE: To study the chemical constituents with antioxidant activity from mulberry leaf. METHODS: Siliga gel column chromatography was used to isolate, and their structures were identified by spectras. METHODS: Isolated constituents were tested in vitro for antioxidant activity against 1, 1-diphenyl -2-picrylhydrazyl (DPPH) and 2, 2' -azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) (ABTS+) radicals. RESULTS: Four known flavonoids were isolated from mulberry leaf and their structures were identified as kaempferol-3-O-beta-D-glucopyranoside (I), quercetin-3-O-beta-D-glucopyranoside (II), quercitrin (III), morin-3-O-beta-D-glucopyranoside (IV). All these compounds showed DPPH and ABTS+ radicals scavenging activity. CONCLUSION: Compound IV has the strongest ABTS+ radicals scavenging effects.
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