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  • Title: Executive function, coping, and behavior in survivors of childhood acute lymphocytic leukemia.
    Author: Campbell LK, Scaduto M, Van Slyke D, Niarhos F, Whitlock JA, Compas BE.
    Journal: J Pediatr Psychol; 2009 Apr; 34(3):317-27. PubMed ID: 18667478.
    Abstract:
    OBJECTIVE: To examine the role of executive function in coping and behavioral outcomes in childhood acute lymphocytic leukemia (ALL) survivors. METHODS: We examined associations among several domains of executive function (working memory, behavioral inhibition, cognitive flexibility, and self-monitoring), coping, and emotional/behavioral problems in 30 children and adolescents ages 10- to 20-years old who completed treatment for ALL and 30 healthy controls matched on age and sex. RESULTS: We found partial support for our hypothesis that performance on executive function measures is associated with strategies used to cope with stress, and emotional and behavioral problems in ALL survivors. CONCLUSIONS: Findings suggest that executive function impairment may be associated with difficulties in coping and emotion regulation in a subgroup of children treated for ALL. Directions for future research on executive function deficits and coping skills in survivors of pediatric ALL are suggested.
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