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  • Title: [Leydig cell tumor: presentation of 3 new cases with a benign course].
    Author: Javier Navarro F, Cozar JM, Nistal M, Martínez-Piñeiro L, Moreno JA, Jiménez J, Cisneros J, de la Peña J, Martínez-Piñeiro JA.
    Journal: Arch Esp Urol; 1991 Mar; 44(2):145-50. PubMed ID: 1867489.
    Abstract:
    Three cases of Leydig cell tumor are described. Patient ages were 27, 44 and 55 years, respectively. The first two patients consulted for a testicular mass and the third patient presented with gynecomastia, an incidental finding during the ultrasound work up of a hydrocele. Hormonal evaluation revealed a marked serum testosterone level in one case, whereas in another case it fell within the lower limits of normal ranges. No evidence of dissemination was observed in all patients. Treatment was by radical inguinal orchiectomy in all patients. The pathological analysis of the surgical specimens revealed Leydig cell tumor with no histologic evidence of malignancy. A follow-up of 32, 14 and 10 months, respectively, revealed no evidence of tumor recurrence in all patients. The clinical and histologic features and treatment of this disease process are described.
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