These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Chemoenzymatic acylation of aminoglycoside antibiotics.
    Author: Llewellyn NM, Spencer JB.
    Journal: Chem Commun (Camb); 2008 Aug 28; (32):3786-8. PubMed ID: 18685777.
    Abstract:
    The chemoenzymatic installation of the clinically valuable (S)-4-amino-2-hydroxybutyryl side chain onto a number of 2-deoxystreptamine-containing aminoglycosides is described using the purified Bacillus circulans biosynthetic enzymes BtrH and BtrG in combination with a synthetic acyl-SNAC surrogate substrate.
    [Abstract] [Full Text] [Related] [New Search]