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Pubmed for Handhelds

PUBMED FOR HANDHELDS

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  • Title: Epidural steroid injections do not induce weight gain.
    Author: Brill S, Swartz A, Brill G.
    Journal: Curr Drug Saf; 2007 May; 2(2):113-6. PubMed ID: 18690956.
    Abstract:
    OBJECTIVE: Neuraxial administration of steroids have been used in clinical practice for more than 50 years and have a well defined place in the treatment of radicular low back pain. However, steroids have widespread effects on almost all body systems, such as suppression of the pituitary-adrenal axis with consecutive weight gain and osteoporosis. METHODS: We prospectively evaluated the effect of three consecutive epidural steroid injections with 40 mg. methylprednisolone acetate once monthly for 3 months on weight gain. The study population included 108 patients, who attended the pain clinic for chronic low back pain. Completed data were available for 100 patients. RESULTS: We found no significant change in weight after administration of a series of three-epidural steroid injections. DISCUSSION: It appears that neuraxial steroids administration doesn't induce weight gain.
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