These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Analytical and semi-preparative enantioseparation of organic phosphonates on a new immobilized amylose based chiral stationary phase.
    Author: Zhang Y, Song B, Bhadury PS, Hu D, Yang S, Shi X, Liu D, Jin L.
    Journal: J Sep Sci; 2008 Sep; 31(16-17):2946-52. PubMed ID: 18693321.
    Abstract:
    Two chiral stationary phases derived from derivatized amylose (Chiralpak AD-H and Chiralpak IA) have been used to separate the enantiomers of new diethyl benzamidoarylmethylphosphonates. The data obtained indicate that all the studied compounds could be easily baseline resolved on both columns. Owing to the different techniques involved in their preparation, the two stationary phases differ in their abilities to effect enantiomeric separation. The semi-preparative separation of all compounds was executed successfully in n-hexane/EtOH on the new immobilized Chiralpak IA column. The analytical assessment of the enantiomeric excess values of all collected fractions was higher than 97%. The stereochemical configuration for the F1 fraction of a diethyl benzamidoarylmethylphosphonate was determined by X-ray diffraction structure analysis.
    [Abstract] [Full Text] [Related] [New Search]