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  • Title: Total synthesis of (-)-kendomycin.
    Author: Lowe JT, Panek JS.
    Journal: Org Lett; 2008 Sep 04; 10(17):3813-6. PubMed ID: 18698784.
    Abstract:
    An enantioselective synthesis of (-)-kendomycin is described and is based on the application of the organosilane-based [4 + 2]-annulation strategy for the assembly of the C1a-C10 fragment. An underutilized samarium(II) iodide-assisted cyclization (intramolecular Barbier-type reaction) is employed to afford the protected macrocycle.
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