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  • Title: Glycopeptide insensitive Staphylococcus aureus subdural empyema treated with linezolid and rifampicin.
    Author: Gallagher RM, Pizer B, Ellison JA, Riordan FA.
    Journal: J Infect; 2008 Nov; 57(5):410-3. PubMed ID: 18703232.
    Abstract:
    A 4-year-old boy had surgical debulking of a cerebral astrocytoma followed by chemotherapy. He developed a subdural empyema with a teicoplanin and methicillin resistant Staphylococcus aureus. He was successfully treated with surgical drainage and 6 weeks of antibiotic therapy which included linezolid, rifampicin and metronidazole. Linezolid may be successful in treating other CNS infections caused by antibiotic resistant gram-positive organisms.
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