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  • Title: Preparation of highly photosensitizing liposomes with fullerene-doped lipid bilayer using dispersion-controllable molecular exchange reactions.
    Author: Ikeda A, Sue T, Akiyama M, Fujioka K, Shigematsu T, Doi Y, Kikuchi J, Konishi T, Nakajima R.
    Journal: Org Lett; 2008 Sep 18; 10(18):4077-80. PubMed ID: 18707108.
    Abstract:
    Fullerene-containing liposomes with high photosensitization ability were prepared. Disaggregated fullerenes were efficiently injected into the bilayer of liposomes by a phototriggered molecular exchange reaction. These liposomes showed far higher photoreactivity than liposomes thermally produced by heating and microwave irradiation. This result indicates that control of self-aggregation of fullerene leads to a high quantum yield for the photoreaction because of the suppression of self-quenching of photoexcited fullerenes.
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