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  • Title: Vincristine-induced fatal neuropathy in non-Hodgkin's lymphoma.
    Author: Tarlaci S.
    Journal: Neurotoxicology; 2008 Jul; 29(4):748-9. PubMed ID: 18754106.
    Abstract:
    The vinca alkaloids are neurotoxic, usually causing a peripheral neuropathy, but cranial neuropathies are rare as side effects. We describe a case of vincristine-induced multiple cranial and autonomic neuropathy, and sensory-motor axonal peripheral neuropathy (pan-neuropathy), which is an extremely rare fatal complication of this drug. The patient developed fulminant cranial, peripheral and significant autonomic neuropathy.
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