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  • Title: [Value of intraoperative fine-needle aspiration cytology and histopathologic biopsy in the diagnosis of pancreatic cancer].
    Author: Zhao DB, Wang Y, Shan Y, Wang CF, Shao YF, Zhao P.
    Journal: Zhonghua Zhong Liu Za Zhi; 2008 Mar; 30(3):231-3. PubMed ID: 18756944.
    Abstract:
    OBJECTIVE: To investigate the clinical value of intraoperative aspiration cytology and histopathologic biopsy in the diagnosis of pancreatic cancer. METHODS: 142 patients with suspected pancreatic carcinoma underwent surgical exploration and the data were retrospectively analyzed. Chi-square test (chi2) was used to compare the accuracy between fine-needle aspiration cytology and histopathologic biopsy. RESULTS: Of the 192 patients with suspected pancreatic carcinoma, 80 were confirmed by histological biopsy and 87 by fine-needle aspiration cytology, with an accuracy rate of 83.8% and 93.1%, respectively. There was a statistically significant difference between these two groups (P = 0.027). No perioperative surgical complication was observed in this series. CONCLUSION: Intraoperative aspiration cytology and histopathologic biopsy was safe and helpful with a high accuracy for the diagnosis of pancreatic carcinoma.
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