These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Repeating an abnormal prostate-specific antigen (PSA) level: how relevant is a decrease in PSA?
    Author: Connolly D, Black A, Murray LJ, Nambirajan T, Keane PF, Gavin A.
    Journal: Prostate Cancer Prostatic Dis; 2009; 12(1):47-51. PubMed ID: 18762815.
    Abstract:
    To examine the practice of repeating an abnormal prostate-specific antigen (PSA) level before proceeding to prostate biopsy, we assessed the pattern of PSA change following an initially raised (>or=4.0 ng ml(-1)) PSA, and the relationship of this to prostate cancer diagnosis. In 7052 men, 71.2% with initially raised PSA had a reduction in PSA, with values <4.0 ng ml(-1) in 37.8%. A total of 43.0% of men with prostate cancer showed a PSA decrease below their baseline level. Short-term decreases in PSA may occur in men with prostate cancer, including high-grade cancer, and so should not influence the decision to proceed to prostate biopsy.
    [Abstract] [Full Text] [Related] [New Search]