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  • Title: Word deafness as a cortical auditory processing deficit: a case report with MEG.
    Author: Jörgens S, Biermann-Ruben K, Kurz MW, Flügel C, Daehli Kurz K, Antke C, Hartung HP, Seitz RJ, Schnitzler A.
    Journal: Neurocase; 2008; 14(4):307-16. PubMed ID: 18766983.
    Abstract:
    Pure word deafness is a rare disorder dramatically impairing comprehension of spoken language, while auditory functions remain relatively intact. We present a 71-year-old woman with a slowly progressive disturbance of speech perception due to pure word deafness. MRI revealed degeneration of the temporal lobes. A magnetoencephalographic investigation using alternating single tone stimulation showed that N100 was followed by a second transient response and was abnormally prolonged up to 600-700 ms. We conclude that auditory processing is disturbed at long latency ranges following the N100, which may result in the clinical presentation of pure word deafness.
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