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  • Title: Evaluation of a new bladder tumor marker.
    Author: Grossman HB, Liebert M, Sakakibara N, Wedemeyer GA, Stein JA, Washington RW.
    Journal: Urol Clin North Am; 1991 Aug; 18(3):509-13. PubMed ID: 1877113.
    Abstract:
    Two monoclonal antibodies have been developed that bind to a shed bladder tumor-associated antigen. Preliminary data have demonstrated that antigen-positive tumors shed detectable amounts of antigen in the urine while antigen-negative tumors do not. This antigen may be differentially metabolized by normal and malignant urothelial cells. Further characterization of this antigen and its evaluation as a urinary marker for antigen positive bladder cancers is continuing.
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