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  • Title: Antifungal cyclic depsipeptide, eujavanicin A, isolated from Eupenicillium javanicum.
    Author: Nakadate S, Nozawa K, Sato H, Horie H, Fujii Y, Nagai M, Hosoe T, Kawai K, Yaguchi T.
    Journal: J Nat Prod; 2008 Sep; 71(9):1640-2. PubMed ID: 18771240.
    Abstract:
    In the course of searching for new antifungal agents, a new cyclic depsipeptide, eujavanicin A (1), was isolated from Eupenicillium javanicum as an antifungal agent against the human pathogenic filamentous fungus Aspergillus fumigatus. The structure of 1 was established by spectroscopic and chemical investigations. The absolute stereochemistry was elucidated by Marfey's method and by chiral HPLC analysis.
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