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  • Title: Comparative study of higher-order aberrations after conventional laser in situ keratomileusis and laser epithelial keratomileusis for myopia using the technolas 217z laser platform.
    Author: Kirwan C, O'Keefe M.
    Journal: Am J Ophthalmol; 2009 Jan; 147(1):77-83. PubMed ID: 18775529.
    Abstract:
    PURPOSE: To examine changes in higher-order aberrations (HOAs) after PlanoScan laser in situ keratomileusis and (LASIK) and laser epithelial keratomileusis (LASEK). DESIGN: Prospective, comparative study. METHODS: Myopic patients undergoing LASIK (65 eyes of 36 patients) and LASEK (50 eyes of 28 patients) at a private practice were selected randomly. Surgery was performed using the Technolas 217z laser (Bausch & Lomb, Surrey, United Kingdom). Main outcome measures included uncorrected visual acuity (UCVA), manifest refractive spherical equivalent (MRSE), and aberrometry (Zywave; Bausch & Lomb, Rochester, New York, USA) and were recorded before surgery and at three and 12 months after surgery. RESULTS: There was no statistical difference between both groups in terms of MRSE (P = .91), ablation depth (P = .47), scotopic pupil size (P = .38), or optical zone (P = .07). Before surgery, there was no statistical difference in root mean square (RMS) of total (P = .70), third- (P = .79), fourth- (P = .23), and fifth- (P = .33) order aberrations and individual terms. Three months after surgery, RMS of total HOA was raised significantly more (P = .03) after LASIK (1.46-factor increase) than LASEK (1.25-factor increase). One year after surgery, a reduction in total HOAs was observed in 13.8% of LASIK- and 48.5% of LASEK-treated eyes compared with preoperative levels. CONCLUSIONS: Postoperative increases in total HOA and vertical coma were significantly greater in LASIK- than in LASEK-treated eyes. Postoperative reduction in total HOAs was observed in a number of eyes with high preoperative levels and occurred more frequently in LASEK-treated eyes.
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