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  • Title: Synthesis and incorporation of fluorescent C-nucleoside analogue into oligodeoxyribonucleotides.
    Author: Ozaki H, Kawai T, Kuwahara M, Sawai H.
    Journal: Nucleic Acids Symp Ser (Oxf); 2008; (52):371-2. PubMed ID: 18776408.
    Abstract:
    Fluorescent nucleoside analogues were synthesized and derived to protected nucleoside phosphoramidite. The nucleoside analogue bearing 3-aminobenzonitrile was sensitive to the surrounding environment. 3-Aminobenzonitrile is a similar size with pyrimidine base. Therefore, it is expected that the nucleoside little perturbs the formation of duplex. This nucleoside could be incorporated into DNA.
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