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  • Title: One or two enzyme-linked immunosorbent assay tests on the first serum sample for initial diagnosis of HIV-1 infection?
    Author: Costagliola D, Damond F, Palmer P, Rouzioux C, Brun-Vezinet F.
    Journal: AIDS; 2008 Oct 01; 22(15):2042-4. PubMed ID: 18784468.
    Abstract:
    In France, the first sample for the initial diagnosis of HIV-1 infection must be tested with two antibody assays: one being an enzyme-linked immunosorbent assay. If one is positive, confirmation tests are performed. We evaluated the performance of initial diagnostic strategies based on the use of one versus two enzyme-linked immunosorbent assay tests, either an antigen-antibody test or a simple antibody assay. We found that a single antigen-antibody test was more efficient than a combination of the two tests.
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