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  • Title: [Measurement of fluidity of membrane lipids in lymphocytes from patients with pulmonary tuberculosis].
    Author: Wang BN.
    Journal: Zhonghua Jie He He Hu Xi Za Zhi; 1991 Apr; 14(2):67-8, 125. PubMed ID: 1879016.
    Abstract:
    The degree of fluidity of cellular membranes was determined by fluorescence polarization analysis using fluorescent probe 1,6-Dipheny-1,3,5-hexatriene (DPH), when embedded in membrane lipid region of intact cells. Results have shown that lymphocytes isolated from patients have a more fluid lipid layer in their cellular membrane (eta = 2.69 +/- 0.77 poise chi +/- s) than lymphocytes isolated from normal health (eta = 3.11 +/- 0.95 poise chi +/- s)(P less than 0.05). Increase in degree of membrane microviscosity was closely correlated with the rise in cells number.
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