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  • Title: Duration of appearance of Vi antigen and Salmonella typhi in blood and urine of infected models.
    Author: Wang DM, Gu XH.
    Journal: Chin Med J (Engl); 1991 Jan; 104(1):46-8. PubMed ID: 1879196.
    Abstract:
    Salmonella typhi (S typhi) infected models were established to evaluate the latex agglutination test (LAT) and staphylococcal coagglutination test (SCT) for the detection of S typhi Vi antigen in blood and urine. Antigens in serum or urine were detected within 7 days after infection with positive cultures, and decreased in 2 weeks. LAT and SCT were positive in 7 mice with no bacteria isolation from blood and urine but their spleen aspirates yielded S typhi. Both tests are rapid and sensitive and may be used for the diagnosis of typhoid infection, especially in partially treated patients when their blood cultures are negative.
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