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  • Title: Borrelia burgdorferi and different types of morphea.
    Author: Aberer E, Klade H, Stanek G, Gebhart W.
    Journal: Dermatologica; 1991; 182(3):145-54. PubMed ID: 1879581.
    Abstract:
    Thirty patients with different clinical manifestations of morphea (circumscribed scleroderma) were investigated for serum antibodies against Borrelia burgdorferi determined by ELISA and Western blot analysis. Forty-six percent of the patients were seropositive. Western blots confirmed the ELISA results in 10 of 25 patients (40%), showing a reactivity pattern which can be seen in the course of Lyme borreliosis. In some cases the outcome after antibiotic treatment suggests a direct correlation between the further development of skin lesions and Borrelia infection. Because of these findings we suggest some morphea types to be possibly due to a B. burgdorferi infection.
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