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  • Title: Assessment of the direct agglutination test, fast agglutination screening test, and rK39 dipstick test for the sero-diagnosis of visceral leishmaniasis in Syria.
    Author: Al-Nahhas SA, Al-Taweel AA, Al-Taweel MA.
    Journal: Saudi Med J; 2008 Sep; 29(9):1250-4. PubMed ID: 18813406.
    Abstract:
    OBJECTIVE: To evaluate the performances of 3 serological assays (direct agglutination test [DAT], fast agglutination screening test [FAST], recombinant protein [rK39] dipstick) test for use in primary care, for the diagnosis visceral leishmaniasis (VL) in Syria. METHODS: We utilized 267 serum samples obtained during 2007 from patient groups confirmed and suspected VL, confirmed cutaneous leishmaniasis, toxoplasmosis from endemic areas in Syria and control samples, and applied the 3 serological tests in the Damascus University, Damascus and Health laboratories at the same time, on these samples. RESULTS: Our data show that the tests were very sensitive, where the DAT was the most specific followed by FAST, then rK39 dipstick. CONCLUSION: Our study confirmed that all the tests performed well, and proved to be very important sero-diagnosis tools for visceral leishmaniasis.
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