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  • Title: Neural tonotopy in cochlear implants: an evaluation in unilateral cochlear implant patients with unilateral deafness and tinnitus.
    Author: Vermeire K, Nobbe A, Schleich P, Nopp P, Voormolen MH, Van de Heyning PH.
    Journal: Hear Res; 2008 Nov; 245(1-2):98-106. PubMed ID: 18817861.
    Abstract:
    In cochlear implants, the signal is filtered into different frequency bands and transmitted to electrodes along the cochlea. In this study the frequency-place function for electric hearing was investigated as a means to possibly improve speech coding by delivering information to the appropriate cochlear place. Fourteen subjects with functional hearing in the contralateral ear have been provided with a MED-EL cochlear implant in the deaf ear in order to reduce intractable tinnitus. Pitch scaling experiments were performed using single-electrode, constant-amplitude, constant-rate stimuli in the implanted ear, and acoustic sinusoids in the contralateral ear. The frequency-place function was calculated using the electrode position in the cochlea as obtained from postoperative skull radiographs. Individual frequency-place functions were compared to Greenwood's function in normal hearing. Electric stimulation elicited a low pitch in the apical region of the cochlea, and shifting the stimulating electrode towards the basal region elicited increasingly higher pitch. The frequency-place function did not show a significant shift relative to Greenwood's function. In cochlear implant patients with functional hearing in the non-implanted ear, electrical stimulation produced a frequency-place function that on average resembles Greenwood's function. These results differ from previously derived data.
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