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  • Title: Free fatty acid receptor family: novel targets for the treatment of diabetes and dyslipidemia.
    Author: Bernard J.
    Journal: Curr Opin Investig Drugs; 2008 Oct; 9(10):1078-83. PubMed ID: 18821469.
    Abstract:
    Free fatty acids (FFAs) fuel physiological processes in various tissues, such as skeletal muscle, the heart, liver and pancreas. Malfunction of FFA-mediated signaling pathways, as well as FFA metabolism, has been correlated to pathologies such as type 2 diabetes and dyslipidemia. The recent deorphanization of the FFA receptor family has drawn attention to these G-protein-coupled receptors as potential therapeutic targets for the treatment of metabolic diseases.
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