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  • Title: Synthesis and antibacterial activities of novel oxazolidinones having cyclic sulfonamide moieties.
    Author: Kim SJ, Jung MH, Yoo KH, Cho JH, Oh CH.
    Journal: Bioorg Med Chem Lett; 2008 Nov 01; 18(21):5815-8. PubMed ID: 18842403.
    Abstract:
    The synthesis of a new series of oxazolidinones having cyclic sulfonamide moieties is described. Their in vitro antibacterial activities against both Gram-positive and Gram-negative bacteria were tested and the effect of substituents on the oxazolidinone ring was investigated. A particular compound 15g having [1,2,5]thiadiazolidin-1,1-dioxide moiety showed the most potent antibacterial activity.
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