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  • Title: [Mechanism of oxidative phosphorylation. I. Role of the respiratory chain].
    Author: Shpakov AA, Kosarev AV.
    Journal: Biofizika; 1976 Nov; 21(6):1046-53. PubMed ID: 188492.
    Abstract:
    Mitochondria of white rat brain increased the respiration on succinate in response to ADP addition; in the presence of after NADH the respiration remained unchanged or decreased ofter addition ADP. When organelles were suspended in water distilled in the concentration of 3 mg of protein/ml and kept at melting ice temperature for 24 hours the response of mitochondria to ADP was not changed. Stechiometric relation between the number of electron of the oxidized substrate and absorbed by oxygen depended on ADP during succinate oxidation and did not change on NADH. ADP phosphorylation is suggested to proceed on the stage of the substrate dehydrogenation, rather than on the cytochrome part of the respiratory chain.
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