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  • Title: Functional cloning of a Dictyostelium discoideum cDNA encoding GMP synthetase.
    Author: Van Lookeren Campagne MM, Franke J, Kessin RH.
    Journal: J Biol Chem; 1991 Sep 05; 266(25):16448-52. PubMed ID: 1885577.
    Abstract:
    A functional cloning procedure has been used to recover a cDNA coding for the GMP synthetase of Dictyostelium discoideum. The enzyme is encoded by a single gene, which is actively transcribed during growth, but not during development. The open reading frame encodes a protein of 718 amino acids with a predicted molecular mass of 79.6 kDa. The Dictyostelium enzyme has extensive homology with the GMP synthetase of Escherichia coli and regional homology to other glutamine amidotransferases.
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