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  • Title: [Registration of the first human vaccine against the highly pathogenic avian influenza A(H5N1) virus: considerations].
    Author: de Jong JC, Osterhaus AD.
    Journal: Ned Tijdschr Geneeskd; 2008 Sep 27; 152(39):2113-5. PubMed ID: 18856026.
    Abstract:
    Since its emergence in 1997, the highly pathogenic avian influenza A(H5N1) virus has posed the threat of causing a human pandemic. The question is whether it is feasible and advisable to attempt to give the population a certain degree of basic immunity to this virus. The recent development of effective adjuvants, which culminated this year in the approval of such a vaccine for human use in the European Union, indicates that the approach is possible, although many logistical problems remain. Pre-pandemic vaccination could be considered for the total population or for the most vulnerable groups, i.e. individuals receiving annual influenza vaccination. Another option is stock-piling vaccine, preferably separately from the adjuvant.
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