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  • Title: [Use of DNA amplification by PCR in the study of the hypervariable region (VNTR) in a forensic medicine setting. Experience with 2 systems: Apo B and YNZ 22].
    Author: Giorgetti R, Tagliabracci A, Cingolani M, Ferrara SD.
    Journal: Boll Soc Ital Biol Sper; 1991 Jan; 67(1):25-30. PubMed ID: 1888472.
    Abstract:
    The PCR method has been applied to amplify two Variable-number-Tandem-Repeat (VNTR) sequences. The high polymorphism of these VNTR systems can be usefully applied in medical legal fields such as paternity testing and individual identification. The VNTR systems utilized were: ApoB and YNZ 22. The study was conducted on a three-generation family of thirteen members, whose relationship was previously established using conventional blood systems. The results confirm the Mendelian inheritance of the alleles found and the suitability of the PCR method for forensic purposes.
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