These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Seroepidemiological study of leprosy in a highly endemic population of south India based on an ELISA using synthetic PGL-I.
    Author: Krishnamurthy P, Rao PS, Reddy BN, Subramanian M, Dhandayudapani S, Bhatia V, Neelan PN, Dutta A.
    Journal: Int J Lepr Other Mycobact Dis; 1991 Sep; 59(3):426-31. PubMed ID: 1890366.
    Abstract:
    As part of a continuing longitudinal immuno-epidemiological study, blood samples were collected by finger prick from 4243 individuals living in a highly endemic area for leprosy in South India. The samples were tested for IgM antibodies against phenolic glycolipid-I using an ELISA. Seropositivity defined as optical density greater than or equal to 0.2000 was marginally higher in the age group 10-30 years and in females. There was no evidence for a higher level in contacts than in non-contacts. The future prospect for the large scale use of this ELISA in high-endemic populations in special epidemiological investigations or routine control programs as a serological tool to detect leprosy infection appears questionable.
    [Abstract] [Full Text] [Related] [New Search]