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  • Title: Drug and immuno-diagnostic resistant amoebic liver abscess in Ibadan: an elucidation of a possible mechanism.
    Author: Abioye AA.
    Journal: J Trop Med Hyg; 1976 Nov; 79(11):252-5. PubMed ID: 189058.
    Abstract:
    A thick fibrous walling of amoebic abscess of the liver is very rare. Using as a basis the case of drug and immunodiagnostic resistant amoebic liver abscess in an adult Nigerian, an account is given of the possible mechanisms for such therapeutic and diagnostic failure. A theory of blood-abscess cavity barrier is postulated and suggested as a mechanism for the constant failure to detect antibodies to E. histolytica in the small percentage of cases of amoebic liver abscess (Morris, Powell and Elsdon-Dew, 1970). A study of the rate of diffusion of amoebic excretion/secretion through a thick fibrous tissue or artificial membrane of comparable properties is strongly advocated.
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