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  • Title: [Evaluation of growth hormone treatment results in children with chronic renal failure--one center experience].
    Author: Szczepańska M, Broll I, Dymon I, Szprynger K.
    Journal: Pol Merkur Lekarski; 2008; 24 Suppl 4():46-50. PubMed ID: 18924502.
    Abstract:
    UNLABELLED: The study aimed at the retrospective evaluation of rhGH treatment results in children with chronic renal failure CRF and short stature treated at Dpt. and Clinic of Pediatrics, Dialysis Unit and Ambulatory in Zabrze, Medical University of Silesia in Katowice. Medical records of 21 children at mean age of 11.0 years (7 girls and 14 boys) were analysed. Eleven children remained on renal replacement therapy. The mean dose of rhGH was 1.1 UI/kg/week). Five children are still on rhGH treatment. RESULTS: Mean growth velocity during rhGH treatment was 15.2 cm/ total period of treatment, 6.98 cm/year. Mean SDS of growth at the beginning of treatment was: -3.25, at the end of treatment: -2.76 (p < 0.02). PTH value 123.6 pg/ml, at the end of treatment 241.29 pg/mL (p < 0.05). CONCLUSION: RhGH treatment in children with CRF gives the opportunity to gain the final height compared to healthy children.
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