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  • Title: New diterpenoids and the bioactivity of Erythrophleum fordii.
    Author: Tsao CC, Shen YC, Su CR, Li CY, Liou MJ, Dung NX, Wu TS.
    Journal: Bioorg Med Chem; 2008 Nov 15; 16(22):9867-70. PubMed ID: 18926710.
    Abstract:
    A phytochemical investigation of the leaves of Erythrophleum fordii Oliv. has led to the isolation of three new cassaine-type diterpenoids, erythrofordin A (1), erythrofordin B (2) and erythrofordin C (3), as well as a norcassaine diterpenoid with a novel skeleton, norerythrofordin A (4), and 27 known compounds (5-31). The structures of 1-4 were elucidated on the basis of spectroscopic analysis. Selected compounds from this plant were examined for anti-inflammatory activity. Taraxerol (16) displayed potent NO-reducing activity in microglial cells, and gallic acid (27) exhibited excellent DPPH radical-scavenging effects.
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