These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: A palladium-catalyzed approach to polycyclic sulfur heterocycles.
    Author: Martins A, Lautens M.
    Journal: J Org Chem; 2008 Nov 21; 73(22):8705-10. PubMed ID: 18928320.
    Abstract:
    The synthesis of a variety of polycyclic thiophenes and benzothiophenes is accomplished via a palladium-catalyzed domino ortho-alkylation/direct arylation reaction. An examination of the intramolecular direct arylation of thiophenes suggests that an electrophilic metalation mechanism may be present. This method was further extended to include the synthesis of a (thieno)benzoxepine.
    [Abstract] [Full Text] [Related] [New Search]