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  • Title: [Assessment of conformation changes of immunoglobulin G molecules using a fluorescent probe].
    Author: Pupyrev NP, Matveeva NA, Naumenko VIu, Karpov FF.
    Journal: Biofizika; 1991; 36(2):252-4. PubMed ID: 1892902.
    Abstract:
    A proximate method for conformational changes detection in immunoglobulin G preparations used in research and medical practice is introduced. This method is based on the measurement of IgG-connected 1,8-anilinenaphtalenesulphonate fluorescent probe (ANS) time of damping. When the protein structure is broken fluorescence damping time of IgG-connected ANS rises up.
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