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Title: [Binding of mitoxantrone and ametantrone with poly(d(G-C)) on the B---Z transition, stimulated by NaCl]. Author: Babaian IuS, Manzinii D, Ksodo LE. Journal: Biofizika; 1991; 36(2):266-70. PubMed ID: 1892903. Abstract: Binding of antitumoral preparations mitoxantrone and ametantrone with right and left helical DNA was investigated. B-Z conformational transition stimulated by NaCl in the molecules of poly[d(G.C)].poly[d(G-C)] in complex with mitoxantrone and ametantrone was studied by the method of circular dichroism. It was shown that these compounds disturb B-Z transition but do not inhibit it.[Abstract] [Full Text] [Related] [New Search]