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  • Title: [Proliferative reaction of the epithelium of gastric glands to vagotomy and sympathectomy].
    Author: Mamontov SG, Zakharov VB, Dolinskiĭ GA.
    Journal: Biull Eksp Biol Med; 1991 Apr; 111(4):400-2. PubMed ID: 1893149.
    Abstract:
    By means of autoradiography and metaphase arrest technique 24-hour rhythms and intensity of proliferative processes in the epithelium of gastric glands were studied, as well as morphometric status of these structures after vagotomy and drug sympathectomy in the rat. In both cases the reaction of glandular epithelium appeared with the increase of mitotic activity and the decrease of cell synchronization before the entry into DNA--synthesis and mitosis. The number of epithelial cells in gastric glands became reduced, but after vagotomy, unlike sympathectomy, mainly because of the lack of chief cells. Thus, the trophic control upon the dynamic structure of gastric glands may have different mechanisms of realization for parasympathetic and sympathetic nervous system, probably, through the influence on cell proliferation or differentiation.
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