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  • Title: [Comparative evaluation of the protective effect of sodium valproate, phenazepam and ionol in stress-induced liver damage in rats].
    Author: Nikonorov AA, Tverdokhlib VP.
    Journal: Fiziol Zh (1978); 1991; 37(3):66-70. PubMed ID: 1894054.
    Abstract:
    Ionol, a synthetic antioxidant, limits the stressor liver injury to a greater extent than sodium, valproate and phenazepam, activators of a GABA-ergic link of the stress-limiting organism systems. This injury is exhibited in the organospecific elevated levels of blood enzymes fructosediphosphate aldolase depression of N-demethylase activity of microsomal monooxygenases and a decrease in the amount of cytochromes P-450 and B5.
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