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  • Title: Cholecalciferol metabolites binding in porcine parathyroid glands.
    Author: Cloix JF, Ulmann A, Bachelet M, Funck-Brentano JL.
    Journal: Steroids; 1976 Nov; 28(5):743-9. PubMed ID: 189464.
    Abstract:
    We studied the cytoplasmic and nuclear binding of 25-hydroxychole-calciferol and 1alpha,25-dihydroxycholecalciferol inside porcine parathyroid glands. Both sterols bind to cytoplasmic components, but a specific nuclear uptake was demonstrated only for 1alpha,25-dihydroxycholecalciferol. These findings support the hypothesis that mammalian parathyroid glands are a target organ for some cholecalciferol metabolites.
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