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  • Title: Early diagnosis and successful treatment of acute antibody-mediated rejection of a renal transplant.
    Author: Yang YW, Lin WC, Wu MS, Lee PH, Tsai MK.
    Journal: Exp Clin Transplant; 2008 Sep; 6(3):211-4. PubMed ID: 18954299.
    Abstract:
    Antibody-mediated rejection is a delicate situation. It rarely occurs but when it does, it usually results in graft dysfunction and frequently, graft loss. There has been no standard protocol for treating antibody-mediated rejection, although several therapeutic protocols have been recommended. Early detection and treatments of suspected antibody-mediated rejection can secure the graft and improve its function. Here, we describe a typical case of antibody-mediated rejection in a 46-year-old woman who was successfully treated with intravenous immunoglobulin, plasmapheresis, and the anti-CD20 monoclonal antibody, rituximab.
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