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  • Title: Plasmid-mediated 16S rRNA methylases in aminoglycoside-resistant Enterobacteriaceae isolates in Shanghai, China.
    Author: Wu Q, Zhang Y, Han L, Sun J, Ni Y.
    Journal: Antimicrob Agents Chemother; 2009 Jan; 53(1):271-2. PubMed ID: 18955532.
    Abstract:
    High-level resistance to aminoglycosides produced by 16S rRNA methylases in Enterobacteriaceae isolates was investigated. The prevalences of armA in Escherichia coli, Klebsiella pneumoniae, and Enterobacter cloacae were 0.6%, 3.0%, and 10%, respectively. rmtB was more prevalent than armA. Pulsed-field gel electrophoresis patterns indicated that armA and rmtB have spread horizontally and clonally.
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