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  • Title: Chromatid cohesion: acetylation joins the sisters.
    Author: Tanaka K, Watanabe Y.
    Journal: Curr Biol; 2008 Oct 14; 18(19):R917-9. PubMed ID: 18957238.
    Abstract:
    The replication-fork-associated protein Eco1 is required for the establishment of sister chromatid cohesion, which plays an essential role in faithful chromosome segregation. Three recent studies in yeast and humans reveal that the acetyltransferase activity of Eco1 targets the cohesin subunit Smc3 to facilitate the establishment of cohesion.
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