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  • Title: A case of IgG4-associated cholangitis and autoimmune pancreatitis responsive to corticosteroids.
    Author: Small AJ, Loftus CG, Smyrk TC, Baron TH.
    Journal: Nat Clin Pract Gastroenterol Hepatol; 2008 Dec; 5(12):707-12. PubMed ID: 18957952.
    Abstract:
    BACKGROUND: A 72-year-old male presented to the emergency department with epigastric pain, anorexia and progressive jaundice of 1 week's duration. He had no prior history of gastrointestinal illness, diabetes or cancer. He did not smoke or consume alcohol. He did have a family history of colon and bone cancer. INVESTIGATIONS: Biochemical and serologic studies, CT scan, abdominal ultrasound, endoscopic ultrasound, endoscopic retrograde cholangiopancreatography, biliary cytology, pancreas needle biopsies and immunohistochemical stainings. DIAGNOSIS: Autoimmune pancreatitis with IgG(4)-associated sclerosing cholangitis affecting the extrahepatic biliary ducts and mimicking primary sclerosing cholangitis and cholangiocarcinoma. MANAGEMENT: Corticosteroids and immunomodulatory therapy.
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